Pennsylvania State Route 501, Lancaster County

Roads of the Mid-South & West > Highways of the Commonwealth of Pennsylvania > Pennsylvania State Route 501 > Pennsylvania State Route 501, Lancaster County

Pennsylvania State Route 501
Lancaster County

Pennsylvania State Route 501 is a north-south highway in Northern Lancaster County. It runs from U.S. Rt. 222/Pennsulvania State Route 272, at Lancaster, to the Lebanon/Lancaster County Line, near Brickerville.

PA St Rt 501 passes through the following towns in Lancaster County.
Lancaster

Neffsville
Kissel Hill
Lititz
Birckerville

PA St Rt 501 is multi-plexed in Lancaster County.
U.S. Rt. 222, at Lancaster.
Pennsylvania State Route 722, at Neffsville.
Pennsylvania State Route 772, at Lititz.

PA St Rt 501 crosses the following highways in Lancaster County.
U.S. Rt. 222, at Lancaster.
Pennsylvania State Route 272, at Lancaster.
U.S. Rt. 30, at Lancaster.
U.S. Rt. 222, at Lancaster.
Pennsylvania State Route 722, at Neffsville.
Pennsylvania State Route 722, at Neffsville.
Pennsylvania State Route 772, at Lititz.
Pennsylvania State Route 772, at Lititz.
U.S. Rt. 322, at Brickerville.
Interstate 76 (Pennsylvania Turnpike), near Brickerville. (NO Interchange)

A guide marker on NB U.S. Rt. 222/PA St Rt 272.

A junction marker on NB U.S. Rt. 222/PA St Rt 272.

NB PA St Rt 501 north of Oregon Pike

NB PA St Rt 501 at U.S. Rt. 30.

A BGS on NB PA St Rt 501.

21 October 2025