U.S. Federal Route 15 is a north-south highway in Eastern Cumberland County. It runs from the Cumberland/York County Line, near Grantham, to the Cumberland/Perry County Line, near Summerdale. U.S. Rt. 15 passes through the following towns in Cumberland County. Grantham Shepherdstown Shiremanstown Camp Hill Wormleysburg Enola Summerdale U.S. Rt. 15 is multi-plexed in Cumberland County. U.S. Rt. 11, from Camp Hill to the Cumberland/Perry County Line. U.S. Rt. 15 intersects the following highways in Cumberland County. Pennsylvania State Route 114, at Shepherdstown. Interstate 76, near Mechanicsburg. Pennsylvania Turnpike, near Mechanicsburg. U.S. Rt. 11, at Camp Hill. Pennsylvania State Route 581, at Camp Hill. Pennsylvania State Route 641, at Camp Hill. Pennsylvania State Route 944, at Enola. Interstate 81, at Summerdale.