U.S. Federal Route 123 runs east-west across Central Oconee County. It runs from the Georgia/South Carolina State Line, near Madison, to the Oconee/Pickens County Line, near Clemson U.S. Rt. 123 passes through the following towns in Oconee County. Westminster
Richland Seneca
Keowee U.S. Rt. 123 is multi-plexed in Oconee County. U.S. Rt. 76, from Westminster to the Oconee/Pickens County Line.
EB U.S Rt. 76/NB U.S. Rt. 123 east of west U.S. Rt. 76. EB U.S. Rt. 76/NB U.S. Rt. 123 near Mimosa Road. EB U.S. Rt. 76/U.S. Rt. 123 near Broad Street. A guide marker in Westminster. A junction marker on SB SC St Rt 11. A guide marker on the ramp from SC SC St Rt 11. EB U.S Rt. 76/NB U.S. Rt. 123 at SC St Rt 11. EB U.S. Rt. 76/NB U.S. Rt. 123 near Richland. EB US. Rt. 76/NB U.S. Rt. 123 near Sheep Farm Road. EB U.S. Rt. 76/NB U.S. Rt. 123 at SC St Rt 28/59. WB U.S. Rt. 76/SC St Rt 28; SB U.S. Rt. 123 at SC St Rt 130. A guide marker on SB SC St Rt 130. EB U.S. Rt. 76/SC St Rt 28; NB U.S. Rt. 123 east of Seneca. EB U.S. Rt. 76/SC St Rt 28; NB U.S. Rt. 123 west of Wells Highway. A guide marker on NB Wells Highway. EB U.S. Rt. 76/SC St Rt 28; NB U.S. Rt. 123 east of Wells Highway. EB U.S. Rt. 76/SC St Rt 28; NB U.S. Rt. 123 at SC St Rt 93. EB U.S. Rt. 76/SC St Rt 28; NB U.S. Rt. 123 east of SC St Rt 93. EB U.S. Rt. 76/SC St Rt 28; NB U.S. Rt. 123 at the Seneca River.