U.S. Federal Route 11W runs east-west across Northeastern Knox County. It runs from U.S. Rt. 11/11E/70; Tennessee State Route 168, in Knoxville, to the Knox/Grainger County Line, near Blaine. U.S. Rt. 11W passes through the following towns in Knox County. Knoxville Skaggston U.S. Rt. 11W is multi-plexed in Knox County. Tennessee State Route 1, from Knoxville to Knox/Grainger County Line. U.S. Rt. 11W crosses the following highways in Knox County. U.S. Rt. 11, at Knoxville. U.S. Rt. 11E, at Knoxville. U.S. Rt. 70, at Knoxville. Tennessee State Route 1, at Knoxville. Tennessee State Route 168, at Knoxville. Interstate 40, at Knoxville. Interstate 640, at Knoxville. (NO Interchange) U.S. Rt. 25W, at Knoxville. (NO Interchange) Tennessee State Route 9, at Knoxville. (NO Interchange)