U.S. Federal Route 441 runs north-south though Knox County. This is one of the main highways in Downtown Knox County. U.S. Rt. 441 passes through the following towns in Knox County. Halls Crossroads Knoxville U.S. Rt. 441 is multi-plexed in Knoxville. Tennessee State Route 71, at Knoxville. Tennessee State Route 33, near Knoxville.
SB U.S. Rt. 441/TN St Rt 33 near Clinch Avenue. A junction marker on EB TN St Rt 62. BGS on EB I-40. A BGS on EB I-40. A BGS om EB I-40. A BGS on SB I-275. A BGS on SB I-275. A BGS on SB I-275. A BGS on SB I-275. A BGS on EB I-640; SB U.S. Rt. 25W/TN St Rt 9.