Virginia Secondary State Route 610 runs east-west across Northeastern Wythe County. It runs from Max Meadows to Wytheville. VA Sec St Rt 610 passes thorugh the following towns in Wythe County. Max Meadows Wytheville VA Sec St Rt 610 is not multi-plexed in Wythe County. VA Sec St Rt 610 crosses the following highways in Wythe County. Virginia State Route 121, at Max Meadows. Interstate 77, at Wytheville. Interstate 81, at Wytheville. (NO INTERCHANGE) U.S. Rt. 52, at Wytheville. (NO INTERCHANGE) U.S. Rt. 11, at Wytheville.