U.S. Federal Route 36 cuts east-west across Sangamon County along with Interstate 72. This is also been called the Central Illinois Expressway. U.S. Rt. 36 passes through the following town in Sangamon County. Springfield
U.S. Rt. 36 is multi-plexed in Sangamon County. Interstate 72, from the Sangamon/Macon County Line to the Sangamon/Morgan County Line.
Interstate 55, from Clear Lake Ave. to 6th Street in Springfield.