U.S. Federal Route 52 runs east-west through the northeastern corner of Iroquois County. U.S. Rt. 52 passes through the following towns in Iroquois County. Effner
Sheldon Iroquois
Donovan
U.S. Rt. 52 is multi-plexed in Iroquois County. U.S. Rt. 24, from the Indiana/Illinois State Line to Sheldon.
U.S. Rt. 45, from near L' Erable to the Kankakee/Iroquois County Line.
U.S. Rt. 52 intersects the following highways in Iroquois County. U.S. Rt. 24, at Sheldon.
EB U.S. Rt. 24/52 near the Illinois/Indiana State Line. WB U.S. Rt. 24/52 at Effner. WB U.S. Rt. 24/52 at the Illinois Welcome Sign. A junction marker on WB U.S. Rt. 24/52. WB U.S. Rt. 52 near Donovan. Here two lines of the Kankakee, Beaverville, and Southern Railroad cross. EB U.S. Rt. 52 north of Donovan. EB U.S. Rt. 52 near a railroad crossing north of Donovan. WB U.S. Rt. 52 near L' Erable. A junction marker on NB U.S. Rt. 45. A junction marker on NB IL St Rt 49. A set of guide markers on NB IL St Rt 49. NB U.S. Rt. 45/WB U.S. Rt. 52 north of IL St Rt 49. NB U.S. Rt. 45/WB U.S. Rt. 52 near Clifton.
