U.S. Federal Route 24 runs east-west across Central Iroquois County. This is the eastern most county that it passes through in Illinois. U.S. Rt. 24 passes through the following towns in Iroquois County. Effner
U.S. Rt. 24 is multi-plexed in Iroquois County. U.S. Rt. 52, from the Illinois/Indiana State Line to near Sheldon.