Indiana State Route 550 runs north-south in Central Knox County. It runs from U.S. Rt. 41/150, at Emison, to U.S. Rt. 50/150, near Wheatland. IN St Rt 550 passes through the following towns in Knox County. Emison Bruceville Wheatland
IN St Rt 550 is not multi-plexed in Knox County. IN St Rt 550 intersects the following highways in Knox County. U.S. Rt. 41, at Emison. U.S. Rt. 150, at Emison.