U.S. Rt. 41 runs north south along the western portion of Knox County. This is a four-lane divided route through the entire county. U.S. Rt. 41 passes through the following town in Knox County. Vincennes
U.S. Rt. 41 is multi-plexed in Knox County. U.S. Rt. 150, from the Knox/Sullivan County Line to just east of Vincennes.
NB U.S. Rt. 41/WB U.S. Rt. 150 north of Oaktown. NB U.S. Rt. 41/WB U.S. Rt. 150 at Oakton. NB U.S. Rt. 41/WB U.S. Rt. 150 south of Oaktown. NB U.S. Rt. 41/WB U.S. Rt. 150 north of IN St Rt 550. A guide marker on WB IN St Rt 550. A junction marker on WB IN St Rt 550. NB U.S. Rt. 41/WB U.S. Rt. 150 at IN St Rt 550. NB U.S. Rt. 41/WB U.S. Rt. 150 north of IN St Rt 67. NB U.S. Rt. 41/WB U.S. Rt. 150 at IN St Rt 67. NB U.S. Rt. 41/WB U.S. Rt. 150 north of west U.S. Rt. 50. BGS on EB U.S. Rt. 50. A BGS on EB U.S. Rt. 50. A BGS on EB U.S. Rt. 50. NB U.S. Rt. 41/WB U.S. Rt. 150 at WB U.S. Rt. 50. A BGS on NB U.S. Rt. 41; WB U.S. Rt. 50/150. A BGS on NB U.S. Rt. 41; WB U.S. Rt. 50/150. NB U.S. Rt. 41; WB U.S. Rt. 50/150 near Washington in Vincennes. EB U.S. Rt. 50/150; SB U.S. Rt. 41 at the stack interchange on Vincennes eastside. NB U.S. Rt. 41 at U.S. Rt. 50/150. NB U.S. Rt. 41 south of U.S. Rt. 50/150. A BGS on NB U.S. Rt. 41/WB U.S. Rt. 50. BGS at a exit in Vincennes. NB U.S. Rt. 41 at Hart Street in Vincennes. A guide marker on SB IN St Rt 441. A BGS on SB U.S. Rt. 41. NB U.S. Rt. 41 at IN St Rt 441. NB U.S. Rt. 41 at Industrial Park Blvd. NB U.S. Rt. 41 north of IN St Rt 241. SB U.S. Rt. 41 near Decker. NB U.S. Rt. 41 at the Gibson/Knox County Line.
