Alternate U.S. Federal Route 41 runs south out of Henderson into southwestern Henderson County. This is the main highway to this portion of the county. ALT. U.S. Rt. 41 passes through the following towns in Henderson County. Henderson
Cedar Grove Rock Springs Cairo Tunnel Hill ALT. U.S. Rt. 41 is multi-plexed in Henderson County. U.S. Rt. 60, at Henderson.
Kentucky State Route 136, at Henderson. ALT. U.S. Rt. 41 intersects the following highways in Henderson County. U.S. Rt. 41, at Henderson. U.S. Rt. 60, at Henderson. Kentucky State Route 351, at Henderson.
Kentucky State Route 136, at Henderson. U.S. Rt. 60, at Henderson. Kentucky State Route 136, at Henderson. Kentucky State Route 285, at Henderson. Kentucky State Route 425, at Henderson. Kentucky State Route 443, near Rock Springs. Kentucky State Route 266, at Rock Springs. Kentucky Secondary State Route 2253, neat Cario. Kentucky State Route 416, near Cario.
A guide marker on WB KY St Rt 351. EB U.S. Rt. 60/NB ALT U.S. Rt. 41 north of 3rd in Henderson. EB U.S. Rt. 60/NB ALT U.S. Rt. 41 south of U.S. Rt. 41 in Henderson. BGS on SB U.S. Rt. 41 in Henderson. A BGS on NB U.S. Rt. 41.
