Missouri State Route 163 is a north-south highway through Central Columbia. It is in Central Boone County. This is the only state highway that passes through Columbia that also leaves the city limits. MO St Rt 163 passes through the following towns in Boone County. Columbia
Pierpont MO St Rt 163 is not multi-plexed in Boone County. MO St Rt 163 intersects the following highways in Boone County. Interstate 70, at Columbia. U.S. Rt. 40, at Columbia. BUSN Loop I-70, at Columbia.
Missouri Secondary State Route K, near Columbia. Missouri Secondary State Route N, at Pierpont. U.S. Rt. 63, near Pierpont.
A junction marker on SB U.S. Rt. 63. NB MO St Rt 163 near University of Missouri. NB MO St Rt 163 at University of Missouri. A junction marker on WB BUSN Loop I-70. NB MO St Rt 163 near Downtown Columbia. A guide marker north of BUSN Loop I-70. A mileage chart on EB I-70/U.S. Rt. 40. A BGS on EB I-70/U.S. Rt. 40. The northern end of MO St Rt 163 in Columbia. The northern end marker.