New York State Route 25A is an east-west highway in Northern Queens County. It runs from near the Queens-Midtown Tunnel to the Queens/Nassau County Line. NY St Rt 25A passes through the following town in Queens County. New York City NY St Rt 25A is not multi-plexed in Queens County. NY St Rt 25A crosses the following highways in Queens County. Interstate 495, at New York City. Interstate 278, at New York City. Grand Central Parkway, at New York City. Interstate 678, at New York City. Interstate 295, at New York City.