Roads of the Mid-South & West > Highways of the State of Ohio > U.S. Federal Route 42, Ohio > U.S. Federal Route 42; Hamilton County, Ohio

U.S. Federal Route 42
Hamilton County

U.S. Federal Route 42 is a north-south highway in Hamilton County. It runs from the Kentucky/Ohio State Line, in Cincinnati, to the Hamilton/Butler County Line, near Highpoint.

U.S. Rt. 42 passes through the following towns in Hamilton County.
Cincinnati

Reading
Sharonville

U.S. Rt. 42 is multi-plexed in Hamilton County.
U.S. Rt. 27, at Cincinnati.
U.S. Rt. 52, at Cincinnati.
U.S. Rt. 127, at Cincinnati.

U.S. Rt. 42 intersects the following highways in Hamilton County.
U.S. Rt. 27, at Cincinnati.
U.S. Rt. 52, at Cincinnati.
TRUCK U.S. Rt. 50, at Cincinnati.
Interstate 71, at Cincinnati.
U.S. Rt. 50, at Cincinnati.
U.S. Rt. 22, at Cincinnati.
U.S. Rt. 27, at Cincinnati.
U.S. Rt. 52, at Cincinnati.
U.S. Rt. 127, at Cincinnati.
Ohio State Route 3, at Cincinnati.
Interstate 471, at Cincinnati.
Interstate 71, at Cincinnati.

Ohio State Route 4, at Cincinnati.
Ohio State Route 562, at Cincinnati.
Ohio State Route 561, at Cincinnati.
Interstate 275, at Sharonville.


The Ohio Welcome Sign on EB U.S. Rt. 42/NB U.S. Rt. 127.

EB U.S. Rt. 42/NB U.S. Rt. 127 at the Ohio Welcome Sign.

EB U.S. Rt. 42/SB U.S. Rt. 127 at the Ohio River.

WB U.S. Rt. 42/SB U.S. Rt. 127 at the Clay Wade Bailey Bridge.

A guide marker in Cincinnati.

A BGS in Cincinnati.

WB U.S. Rt. 42/SB U.S. Rt. 127 at I-71/U.S. Rt. 50.

SB U.S. Rt. 42 at Sycamore Street.

SB U.S. Rt. 42 at 12th Street.

A BGS on NB I-471.

A guide marker on EB Dorchester Ave.

SB U.S. Rt. 42 at Elsinore Place.

A BGS in Cincinnati.

NB U.S. Rt. 42 at I-71.

25 September 2022