Roads of the Mid-South & West > Highways of the Commonwealth of Pennsylvania > Interstate 80, Pennsylavania

Interstate 80

Interstate 80 runs east-west across Central Pennsylvania. It runs from the Pennsylvania/Ohio State Line, near Wheatland, to the New Jersey/Pennsylvania State Line, near Delaware Water Gap. This passes through mostly mountain terrain, and avoids major population areas.

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While in Pennsylvania, I-80 is multi-plexed.

I-80 is multi-plexed with...
...Pennsylvania State Route 66, near Mechanicsville.
...ALT. U.S. Rt. 220, near Milesburg.
...U.S. Rt. 220, from near Zion to Mackeyville.
...TRUCK Pennsylvania State Route 715, at Tannersville.
...U.S. Rt. 209, near Stroudsburg.

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In Pennsylvania, Interstate 80 crosses the following interstates.

Interstate 376, near West Middlesex.

A BGS on WB I-80 for I-376 two miles away.

A BGS one mile from I-376 on WB I-80.

WB I-80 a half mile from I-376.

WB I-80 at I-376.

EB I-80 at I-376.
Photo from: Paul Dienhart
Interstate 79, near, Pardoe.

WB I-80 at SB I-79.

EB I-80 one mile from I-79.
Photo from: Paul Dienhart

EB I-80 at I-79.
Photo from: Paul Dienhart
Interstate 99, near Zion.
Interstate 180, near Milton.

EB I-80 one mile from I-180. (April, 2025)

EB I-80 near I-180. (April, 2025)

EB I-80 at I-180. (April, 2025)
Interstate 81, near Drums.

A BGS on EB I-80 two miles from I-81. (April, 2025)

EB I-80 one mile from I-81. (April, 2025)

EB I-80 at south I-81. (April, 2025)

A BGS on EB I-80 for NB I-81. (April, 2025)

EB I-80 at NB I-81. (April, 2025)
Interstate 476, (Pennsylvania Turnpike-NE Ext), near Hickory Run. (NO Direct Interchange)

A BGS on EB I-80 for I-476. (April, 2025)

A BGS on EB I-80 for I-476. (April, 2025)

EB I-80 at I-476. (April, 2025)
Interstate 380, near Pocono Pines.

EB I-80 two miles from I-380. (April, 2025)

EB I-80 one mile from I-380. (April, 2025)

EB I-80 at I-380. (April, 2025)

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Toll Pazas on I-80 in Pennsylvania.

Delaware Water Gap Toll Plaza, near Delaware Water Gap. (WB Only)

A toll warning sign two miles from the plaza on WB I-80 in New Jersey. (April, 2025)

A toll warning sign one mile from the plaza on WB I-80 in New Jersey. (April, 2025)

A toll payment sign on WB I-80 in New Jersey. (April, 2025)

A toll chart on WB I-80 in New Jersey. (April, 2025)

The Delaware Water Gap Toll Plaza on WB I-80. (April, 2025)

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Branches of I-80 in Pennsylvania.

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EB I-80 crossing the Delaware River.

WB I-80 at the Pennsylvania Welcome Sign.

A set of guide markers on Broad Street in Delaware Water Gap.

A set of guide markers on Broad Street in Delaware Water Gap.

A guide marker on SB U.S. Rt. 209.

A set of guide markers on NB BUSN U.S. Rt. 209/SB PA St Rt 611.

A guide marker on SB PA St Rt 191.

A set of guide markers on NB PA St Rt 611.

EB I-80/NB U.S. Rt. 209 at PA St Rt 191/611.

EB I-80/NB U.S. Rt 209 at BUSN U.S. Rt. 209.

EB I-80 at 9th.

EB I-80 at 9th.

EB I-80 east of PA St Rt 33.

A guide marker on SB PA St Rt 33.

A guide maker on SB PA St Rt 33.

A BGS on SB PA St Rt 33.

A guide marker on SB PA St Rt 611.

A guide marker on SB PA St Rt 611.

A guide marker on SB PA St Rt 611.

EB I-80 at I-380.

EB I-80 west of I-380.

A BGS on EB I-80.

EB I-80 near Long Pond Road.

EB I-80 near Stoney Hollow Road.

EB I-80 east of PA St Rt 115.

EB I-80 at PA St Rt 115.

EB I-80 at the Carbon/Monroe County Line.

EB I-80 west of PA St Rt 115.

EB I-80 near Moseywood Road.

EB I-80 east of I-476.

EB I-80 east of White Haven.

EB I-80 east of PA St Rt 534.

A Pocono welcome sign on EB I-80.

EB I-80 at PA St Rt 437/940.

EB I-80 west of PA St Rt 437/940.

EB I-80 near the White Haven Rest Area.

EB I-80 near Hickory Hills.

EB I-80 east of PA St Rt 309.

EB I-80 at PA St Rt 309.

EB I-80 west of PA St Rt 309.

EB I-80 east of I-81.

EB I-80 west of I-81.

EB I-80 west of St. John.

EB I-80 east of PA St Rt 93.

EB I-80 west of PA St Rt 93.

EB I-80 near Shannon Dr.

EB I-80 near Kraska Road.

EB I-80 near Red Rock Road.

EB I-80 near Tank Road.

EB I-80 at the Columbia/Luzerna County Line.

EB I-80 east of PA St Rt 339.

EB I-80 at the Susquehanna River.

EB I-80 at U.S. Rt. 11.

EB I-80 west of U.S. Rt. 11.

EB I-80 east of PA St Rt 487.

A guide marker on EB U.S. Rt. 11.

A guide marker on EB U.S. Rt. 11.

A BGS on EB U.S. Rt. 11/NB PA St Rt 42.

A BGS on EB U.S. Rt. 11.

A guide marker on WB PA St Rt 54.

A guide marker on WB PA St Rt 54.

EB I-80 east of Mexico Road.

EB I-80 at the Montour/Northumberland County Line.

EB I-80 east of PA St Rt 254.

EB I-80 west of PA St Rt 254.

EB I-80 east of I-180.

A BGS on EB I-180.

A guide marker near Mc Ewensville.

EB I-80 at the Northumberland/Union County Line.

A BGS on NB U.S. Rt. 15.

A guide sign on EB PA St Rt 254.

A BGS on NB U.S. Rt. 15/PA St Rt 147.

A BGS on NB U.S. Rt. 15/PA St Rt 147.

A guide marker for I-80.
Photo from: Paul Dienhart

EB I-80 at M.P. 94.
Photo from: Paul Dienhart

A guide marker for I-80.
Photo from: Paul Dienhart

A BGS on NB I-79.

WB I-80 west of I-79.

WB I-80 west of U.S. Rt. 19.

WB I-80 near Greenfield.

WB I-80 east of I-376/PA St Rt 760.

WB I-80 at I-376/PA St Rt 760.

A WB guide marker.

WB I-80 near Wheatland.

WB I-80 near the Ohio/Pennsylvania State Line.

A welcome sign on EB I-80.
Photo from: Paul Dienhart

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16 September 2025