Pennsylvania State Route 641, Cumberland County

Roads of the Mid-South & West > Highways of the Commonwealth of Pennsylvania > Pennsylvania State Route 641 > Pennsylvania State Route 641, Cumberland County

Pennsylvania State Route 644
Cumberland County

Pennsylvania State Route 641 is an east-west highway in Central Cumberland County. It runs from U.S. Rt. 11/15, at Camp Hill, to the Cumberland/Franklin County Line, near Newburg.

PA St Rt 641 passes through the following towns in Cumberland County.
Camp Hill
Shiremanstown
Mechanicsburg
Locust Point
Carlisle
Plainfield
West Hill
Newville
Green Spring
Newburg

PA St Rt 641 is multi-plexed in Cumberland County.
Pennsylvania State Route 114, at Mechanicsburg.
Pennsylvania State Route 74, at Carlilse.

U.S. Rt. 11, at Carlilse.

Pennsylvania State Route 696, at Newburg.

PA St Rt 641 crosses the following highways in Cumberland County.
U.S. Rt. 11, at Camp Hill.
U.S. Rt. 15, at Camp Hill.
U.S. Rt. 11, at Camp Hill.
Pennsylvania State Route 114, at Mechanicsburg.
Pennsylvania State Route 114, at Mechanicsburg.
Interstate 76, (Pennsylvania Turnpike) at Mechanicsburg. (NO Interchange)
Pennsylvania State Route 174, near Locus Point.
Interstate 81, at Carlilse.
Pennsylvania State Route 74, at Carlilse.
U.S. Rt. 11, at Carlisle.
Pennsylvania State Route 34, at Carlisle.
Pennsylvania State Route 74, at Carlilse.
U.S. Rt. 11, at Carlilse.
Pennsylvania State Route 465, at Carlilse.
Pennsylvania State Route 233, at Newville.
Pennsylvania State Route 696, at Newburg.
Pennsylvania State Route 696, at Newburg.

A guide marker on NB PA St Rt 34.

SB U.S. Rt. 11; NB PA St Rt 74/WB PA St Rt 641 west of PA St Rt 34.

28 August 2025