U.S. Federal Route 22 runs along a expressway through Allegheny County, except for a short segment between the junction with Interstate 376 and the Allegheny/Westmoreland County Line. U.S. Rt. 22 passes through the following town in Allegheny County. Pittsburgh U.S. Rt. 22 is multi-plexed in Allegheny County. U.S. Rt. 30, from near Imperial to near Edgewood. Interstate 376, from near Carnegie to Monroeville.
Branches of U.S. Rt. 22 in Allegheny County. A BGS on EB I-376. A BGS on EB I-376. A BGS on EB I-376. A BGS on EB I-376. A BGS on EB I-376. A BGS on EB I-376. A BGS on EB I-376. A BGS on WB I-376/U.S. Rt. 22-30. A BGS on WB I-376/U.S. Rt. 22-30. EB I-376; EB U.S. Rt. 22/30 near Ridge. EB I-376; EB U.S. Rt. 22/30 at Ridge. EB I-376; EB U.S. Rt. 22/30 two miles from I-79. A guide marker on WB Campbell's Run Road. EB I-376; EB U.S. Rt. 22/30 one mile from I-79. EB I-376; EB U.S. Rt. 22/30 near I-79. EB I-376; EB U.S. Rt. 22/30 before I-79. EB I-376; EB U.S. Rt. 22/30 at I-79. A BGS on NB I-79. A set of BGS's on NB I-79. A BGS on SB I-79. EB I-376; EB U.S. Rt. 22/30 at I-79. EB I-376; EB U.S. Rt. 22/30 at I-79. EB I-376; EB U.S. Rt. 22/30 near Carnegie. EB I-376; EB U.S. Rt. 22/30 near Mansfield Ave. EB I-376; U.S. Rt. 22/30 at PA St Rt 50. EB I-376; EB U.S. Rt. 22/30 near Green Tree. Looking west down I-376; U.S. Rt. 22/30 from the gold tower in the picture above in Green Tree. I-376; U.S. Rt. 22/30 passes through steep grades near Downtown Pittsburgh. The first warning sign for the Fort Pitt Tunnel on EB I-376; EB U.S. Rt. 22/30. A sign for a truck run-away ramp on EB I-376; EB U.S. Rt. 22/30. EB I-376; U.S. Rt. 22/30 at the Truck Run-Away Ramp. EB I-376; NB U.S. Rt. 19; EB U.S. Rt. 22/30 over one mile from I-279. EB I-376; NB U.S. Rt. 19; EB U.S. Rt. 22/30 one mile from I-279. EB I-376/U.S. Rt. 19; EB U.S. Rt. 22/30 near the Fort Pitt Tunnel. Lane markers near the Fort Pitt Tunnel. EB I-376/TK U.S. Rt. 19; EB U.S. Rt. 22/30 at the Fort Pitt Tunnel. EB I-376/TK U.S. Rt. 19; EB U.S. Rt. 22/30 in the Fort Pitt Tunnel. WB I-376/TK U.S. Rt. 19; U.S. Rt. 22/30. EB I-376/TK U.S. Rt. 19; EB U.S. Rt. 22/30 crossing the Monongahela River. EB I-376; U.S. Rt. 22/30; NB TK U.S. Rt. 19 at the Monongahela River. EB I-376; EB U.S. Rt. 22/30 before I-279. WB I-376/TK U.S. Rt. 19; U.S. Rt. 22/30 crossing the Fort Pitt Bridge. EB I-376; U.S. Rt. 22/30; NB TK U.S. Rt. 19 crossing the Fort Pitt Bridge. The Fort Pitt Bridge. EB I-376; EB U.S. Rt. 22/30 near I-279. EB I-376; EB U.S. Rt. 22/30 at I-279. EB I-376; EB U.S. Rt. 22/30 east of I-279. EB I-376; EB U.S. Rt. 22/30 near Grant Street. EB I-376; U.S. Rt. 22/30 at Grant Street. EB I-376; U.S. Rt. 22/30 at the Panhandle Bridge. EB I-376; U.S. Rt. 22/30 at the Liberty Bridge. WB I-376; U.S. Rt. 22/30 at the Liberty Bridge. WB I-376; U.S. Rt. 22/30 east of the Liberty Bridge. EB I-376; U.S. Rt. 22/30 east of the Liberty Bridge. WB I-376; U.S. Rt. 22/30 west of 10th Street. EB I-376; U.S. Rt. 22/30 at the South 10th Street Bridge. WB I-376; U.S. Rt. 22/30 at 10th Street. EB I-376; U.S Rt. 22/30 west of the Birmingham Bridge. EB I-376; U.S. Rt. 22/30 at Forbes Ave. WB I-376; U.S. Rt. 22/30 east of PA St Rt 885. EB I-376; U.S. Rt. 22/30 two miles west of the Squirrel Hill Tunnel. EB I-376; U.S. Rt. 22/30 at the Greenfield Bridge. EB I-376; U.S. Rt. 22/30 at Squirrel Hill. WB I-376; U.S. Rt. 22/30 west of the Squirrel Hill Tunnel. EB I-376; U.S. Rt. 22/30 at the Squirrel Hill Tunnel. EB I-376; U.S. Rt. 22/30 in the Squirrel Hill Tunnel. WB I-376; U.S. Rt. 22/30 in the Squirrel Hill Tunnel. WB I-376; U.S. Rt. 22/30 at the Squirrel Hill Tunnel. EB I-376; U.S. Rt. 22/30 east of the Squirrel Hill Tunnel. EB I-376; U.S. Rt. 22/30 near Edgewood Ave. EB I-376; U.S. Rt. 22/30 at Brinton Road. WB I-376; U.S. Rt. 22/30 west of PA St Rt 8. WB I-376/U.S. Rt. 22 east of PA St Rt 8. EB I-376/U.S. Rt. 22 west of Greensburg Pike. EB I-376/U.S. Rt. 22 west of BUSN U.S. Rt. 22. EB I-376/U.S. Rt. 22 east of PA St Rt 791. EB I-376/U.S. Rt. 22 near Leak Run. WB I-376/U.S. Rt. 22 west of I-76. A BGS on WB I-376/U.S. Rt. 22. A BGS on WB I-376/U.S. Rt. 22. A BGS on WB I-376. A BGS on WB I-76/PA Turn.