Roads of the Mid-South & West > Highways of the State of Indiana > Triple Number U.S. Federal Highways of Indiana > U.S. Federal Route 421, Indiana

U.S. Federal Route 421

United States Federal Route 421 runs north-south across Central Indiana. This highway runs from Michigan City, south to the State of Kentucky, via Indianapolis. Info on U.S. Rt. 421 is broken down by county below.

La Porte County Starke County
Pulaski County White County

Clinton County

Jefferson County

19 September 2020