U.S. Federal Route 60 runs east-west highway across Henderson County. From Henderson west this is the main highway in the county. East of Henderson this highway runs along the Audubon Parkway. This is a free alternative. U.S. Rt. 60 passes through the following towns in Henderson County. Corydon Henderson
Spottsville Reed U.S. Rt. 60 is multi-plexed in Henderson County. Kentucky State Route 136, at Henderson. ALT U.S. Rt. 41, at Henderson.