Missouri State Route 25 is a north-south highway in South Central Cape Girardeau County. Just before it gets to the Cape Girardeau/Scott County Line it heads east-west along the county line to Stoddard County. MO St Rt 25 passes through the following towns in Cape Girardeau County. Jackson
Dutchtown Delta Arbor MO St Rt 25 intersects the following highways in Cape Girardeau County. BUSN Loop I-55, at Jackson. U.S. Rt. 61, at Jackson. Missouri State Route 34, at Jackson. Missouri State Route 72, at Jackson. Missouri Secondary State Route K, near Gordonville. Missouri Secondary State Route Z, near Gordonville. Missouri State Route 74, near Dutchtown. Missouri Secondary State Route A, at Dutchtown. Missouri State Route 77, near Dutchtown. Missouri Secondary State Route EE, at Delta. Missouri Secondary State Route N, at Delta. Missouri Seocndary State Route P, near Delta. Missouri Secondary State Route NN, near Arbor.
A junction marker on SB BUSN Loop I-55/U.S. Rt. 61.
