Interstate 65, IndianaRoads of the Mid-South & West > Highways of the State of Indiana > Interstate 65, Indiana

Interstate 65

Interstate 65 runs north-south along the length of Indiana. This connects the state to the Chicago-Metro Area. Plus, is the direct connection for Chicago and Indianapolis (to each other).

While in Indiana, I-65 is multi-plexed several times.

I-65 is multi-plexed with...

...U.S. Rt. 52, from Lebanon to Indianapolis.

...Interstate 70, in Downtown Indianapolis.

...U.S. Rt. 31, from Sellersburg to Jeffersonville.


I-65 crosses the following interstates in Indiana.

Interstate 90, (Indiana East-West Toll Road) near Lake Station

NB I-65 near I-90.

NB I-65 over one mile from I-90. (September, 2016)

NB I-65 a quarter mile from I-90. (September, 2016)

NB I-65 at I-90. (September, 2016)

Interstate 80, (Borman Expressway) near Gary.
Interstate 94, (Borman Expressway) near Gary.

NB I-65 near I-80/94.

NB I-65 at WB I-80/94.

NB I-65 at EB I-80/94.

NB I-65 over one mile fron I-80/94. (July, 2009)

NB I-65 less than a mile from the frist exit for I-80/94. (July, 2009

NB I-65 near I-80/94. (July, 2009)

NB I-65 at the ramp to EB I-80/94. (July, 2009)

A set of BGS on the ramp to EB I-80/94 from NB I-65/BUSN U.S. Rt. 6. (July, 2009)

NB I-65 near WB I-80/94. (July, 2009)

NB I-65 at WB I-80/94. (July, 2009)

SB I-65 one mile from I-80/94.

SB I-65 one mile from I-80/94. (July, 2018)

SB I-65 near I-80/94.

SB I-65 at I-80/94.

Lane markers on the ramp from SB I-65 to I-80/94.
Interstate 865, at Indianapolis.

A BGS on SB I-65.

SB I-65 near I-865.

SB I-65 at I-865.

A BGS on SB I-65/EB U.S. Rt. 52 over two miles from I-865.

A BGS on SB I-65/EB U.S. Rt. 52 under one mile from I-865.

SB I-65/EB U.S. Rt. 52 near I-865.

SB I-65/EB U.S. Rt. 52 at I-865.

SB I-65 at I-865.
Photo from: Paul Dienhart

SB I-65/EB U.S. Rt. 52 a half mile from I-865.

SB I-65/EB U.S. Rt. 52 at I-865.

Interstate 465, at Indianapolis.

A BGS on NB I-65.

NB I-65 near I-465.

NB I-65 at I-465.

SB I-65 at I-465.

SB I-65 a half mile from I-465.

SB I-65 at I-465.
Interstate 70, at Indianapolis.

NB I-65/EB I-70 three quarters of a mile from their split.

NB I-65/EB I-70 near thier split.

NB I-65/EB I-70 at their split.

SB I-65 under two miles from I-70. (June, 2020)

SB I-65 over one mile from I-70. (June, 2020)

SB I-65 under one mile from I-70. (June, 2020)

SB I-65 near I-70. (June, 2020)

SB I-65 at I-70. (June, 2020)
Interstate 70, at Indianapolis.

SB I-65/WB I-70 one mile from their split.

SB I-65/WB I-70 near their split.

NB I-65 three miles from WB I-70.

NB I-65 over one mile from WB I-70.

NB I-65 near WB I-70.

NB I-65 at WB I-70.

SB I-65 one mile from WB I-70. (June, 2020)

SB I-65 under one mile from WB I-70. (June, 2020)

SB I-65 a half mile from WB I-70. (June, 2020)

SB I-65 at WB I-70. (June, 2020)
Interstate 74, at Indianapolis.
Interstate 465, at Indianapolis.

NB I-65 one mile from I-74/465.

NB I-65 at I-74/465.
Interstate 265, at Clarksville.

NB I-65 one mile from I-265.

NB I-65 a half mile from I-265.

NB I-65 at the interchange with I-265.

NB I-65 at the ramp for I-265.

SB I-65 over a mile from I-265.

SB I-65 near I-265.

SB I-65 at I-265.


I-65 crosses the following interstates in Indiana.

Ohio River Bridge Toll, at Jeffersonville.

NB I-65 at the Ohio River Toll Plaza. (April, 2022)

SB I-65 at the Ohio River Toll Plaza. (April, 2022)

Branches of I-65 in Indiana.


Photos of Interstate 65 as it travels through Indiana.
Select A Section of I-65.


27 January 2024